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Literature summary for 2.7.11.21 extracted from

  • Draghetti, C.; Salvat, C.; Zanoguera, F.; Curchod, M.L.; Vignaud, C.; Peixoto, H.; Di Cara, A.; Fischer, D.; Dhanabal, M.; Andreas, G.; Abderrahim, H.; Rommel, C.; Camps, M.
    Functional whole-genome analysis identifies polo-like kinase 2 and poliovirus receptor as essential for neuronal differentiation upstream of the negative regulator alphaB-crystallin (2009), J. Biol. Chem., 284, 32053-32065.
    View publication on PubMedView publication on EuropePMC
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Activating Compound

Activating Compound Comment Organism Structure
basic fibroblast growth factor bFGF, extracellular stimuli to induce NS-1 cell differentiation Mus musculus
dibutyryl cAMP dbcAMP, extracellular stimuli to induce NS-1 cell differentiation Mus musculus
forskolin extracellular stimuli to induce NS-1 cell differentiation Mus musculus
interleukin-6 IL-6, extracellular stimuli to induce NS-1 cell differentiation Mus musculus
nerve growth factor NGF, extracellular stimuli to induce NS-1 cell differentiation Mus musculus
pituitary adenylate cyclase-activating polypeptide 38 PACAP38, extracellular stimuli to induce NS-1 cell differentiation Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
siRNA
-
 Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + a protein Mus musculus
-
 ADP + a phosphoprotein
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus P53351
-
-

Source Tissue

Source Tissue Comment Organism Textmining
P3/NS1/1-Ag4.1 cell
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + a protein
-
 Mus musculus ADP + a phosphoprotein
-
 ?

Synonyms

Synonyms Comment Organism
Plk2
-
 Mus musculus
polo-like kinase 2
-
 Mus musculus

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Mus musculus