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Literature summary for 2.7.11.20 extracted from

  • Kameshima, S.; Okada, M.; Ikeda, S.; Watanabe, Y.; Yamawaki, H.
    Coordination of changes in expression and phosphorylation of eukaryotic elongation factor 2 (eEF2) and eEF2 kinase in hypertrophied cardiomyocytes (2016), Biochem. Biophys. Rep., 7, 218-224 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.11.20

Activating Compound

Activating Compound Comment Organism Structure
Calmodulin
-
 Mus musculus
Calmodulin
-
 Rattus norvegicus

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ dependent on Mus musculus
Ca2+ dependent on Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + [eukaryotic elongation factor 2] Mus musculus
-
 ADP + [eukaryotic elongation factor 2] phosphate
-
 ?
ATP + [eukaryotic elongation factor 2] Rattus norvegicus
-
 ADP + [eukaryotic elongation factor 2] phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus O08796
-
-
Rattus norvegicus P70531
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein phosphorylation sites at Ser366 and Thr56 Mus musculus
phosphoprotein phosphorylation sites at Ser366 and Thr56 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
cardiac muscle fiber
-
 Mus musculus
-
cardiac muscle fiber
-
 Rattus norvegicus
-
heart
-
 Mus musculus
-
heart
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + [eukaryotic elongation factor 2]
-
 Mus musculus ADP + [eukaryotic elongation factor 2] phosphate
-
 ?
ATP + [eukaryotic elongation factor 2]
-
 Rattus norvegicus ADP + [eukaryotic elongation factor 2] phosphate
-
 ?

Subunits

Subunits Comment Organism
? x * 82000, SDS-PAGE Mus musculus
? x * 82000, SDS-PAGE Rattus norvegicus

Synonyms

Synonyms Comment Organism
eEF2 kinase
-
 Mus musculus
eEF2 kinase
-
 Rattus norvegicus
eEF2K
-
 Mus musculus
eEF2K
-
 Rattus norvegicus
eukaryotic elongation factor 2 kinase
-
 Mus musculus
eukaryotic elongation factor 2 kinase
-
 Rattus norvegicus

General Information

General Information Comment Organism
physiological function cardiac hypertrophy may be regulated at least partly via enzyme-eukaryotic elongation factor 2 signaling pathway Mus musculus
physiological function cardiac hypertrophy may be regulated at least partly via enzyme-eukaryotic elongation factor 2 signaling pathway Rattus norvegicus