Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | required for activity | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
bronchial smooth muscle cell | - |
Mus musculus | - |
tracheal smooth muscle cell | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + myosin regulatory light chain | - |
Mus musculus | ADP + myosin regulatory light chain phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MLCK | - |
Mus musculus |
myosin light chain kinase | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Mus musculus | |
Calmodulin | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | MLCK-deficient mice lack bronchial constrictions in normal and asthmatic airways, while the asthmatic inflammation response is not affected | Mus musculus |
physiological function | myosin light chain kinase acts as a central participant in the contractile signaling module of tonic smooth muscle | Mus musculus |