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Literature summary for 2.7.11.17 extracted from

  • Nimura, T.; Sugiyama, Y.; Sueyoshi, N.; Shigeri, Y.; Ishida, A.; Kameshita, I.
    A minimum size homologue of Ca2+/calmodulin-dependent protein kinase IV naturally occurring in zebrafish (2010), J. Biochem., 147, 857-865.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
-
Danio rerio

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol mainly localized in the nucleus Danio rerio 5829
-
nucleus mainly localized in the nucleus Danio rerio 5634
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
40620
-
calculated from sequence Danio rerio

Organism

Organism UniProt Comment Textmining
Danio rerio Q568I9
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Danio rerio
-
embryo weakly expressed in the embryo at 48 and 72 hours post-fertilization stages, and strongly expressed in the embryo at 96 hours post-fertilization stage Danio rerio
-
neuron
-
Danio rerio
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + histone H1 rat CaMKIV prefers histone H1 over myelin basic protein, while Danio rerio CaMKIV does not Danio rerio ADP + phosphorylated histone H1
-
?
ATP + myelin basic protein rat CaMKIV prefers histone H1 over myelin basic protein, while Danio rerio CaMKIV does not Danio rerio ADP + phosphorylated myelin basic protein
-
?
ATP + syntide-2
-
Danio rerio ADP + phosphorylated syntide-2
-
?
additional information the C-terminal region of rat CaMKIV, which is absent from Danio rerio CaMKIV, is involved in the regulation of both its substrate specificity and its susceptibility to dephosphorylation by nuclear CaMK phosphatase Danio rerio ?
-
?

Synonyms

Synonyms Comment Organism
Ca2+/calmodulin-dependent protein kinase IV
-
Danio rerio
CaMKIV
-
Danio rerio

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
assay at Danio rerio

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
assay at Danio rerio

pI Value

Organism Comment pI Value Maximum pI Value
Danio rerio calculated from sequence
-
7.2

Expression

Organism Comment Expression
Danio rerio weakly expressed in the embryo at 48 and 72 hours post-fertilization stages, and strongly expressed in the embryo at the hours post-fertilization stage up

General Information

General Information Comment Organism
physiological function the enzyme plays some roles in the embryogenesis in zebrafish Danio rerio