Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | hypoxia results in increased nuclear Ca2+-influx and increased CaM kinase IV activity | Cavia porcellus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | the administration of clonidine, an inhibitor of high-affinity nuclear Ca2+-ATPase, prevents the hypoxia-induced increase in nuclear Ca2+-influx and CaM kinase IV activity | Cavia porcellus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | dependent on | Cavia porcellus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cavia porcellus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cerebral cortex | cerebral cortical neuronal nucleus | Cavia porcellus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + cyclic AMP response element binding protein | phosphorylated at Ser133 | Cavia porcellus | ADP + phosphorylated cyclic AMP response element binding protein | - |
? | |
ATP + syntide-2 | - |
Cavia porcellus | ADP + phosphorylated syntide-2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
calcium/calmodulin-dependent protein kinase IV | - |
Cavia porcellus |
CaMK IV | - |
Cavia porcellus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Cavia porcellus | |
Calmodulin | dependent on | Cavia porcellus |