Cloned (Comment) | Organism |
---|---|
expressed in HEK-293T cells | Gallus gallus |
Protein Variants | Comment | Organism |
---|---|---|
K60E | mutant is kinase dead | Gallus gallus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Gallus gallus | 5829 | - |
nucleus | mainly localized in the nucleus | Gallus gallus | 5634 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | dependent on, 2 mM CaCl2 plus 0.001 mM calmodulin induce 69.2% activation of CaMKIV activity | Gallus gallus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
40000 | - |
SDS-PAGE | Gallus gallus |
41300 | - |
estimated from amino acid sequence | Gallus gallus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Gallus gallus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
anti-FLAG-Sepharose chromatography | Gallus gallus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
motoneuron | - |
Gallus gallus | - |
spinal cord | - |
Gallus gallus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + cAMP response element binding protein | - |
Gallus gallus | ADP + phosphorylated cAMP response element binding protein | - |
? | |
ATP + phosphatidylinositol 3-kinase | - |
Gallus gallus | ADP + phosphorylated phosphatidylinositol 3-kinase | - |
? | |
ATP + protein kinase B | - |
Gallus gallus | ADP + phosphorylated protein kinase B | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Ca2+/CaM-dependent protein kinase | - |
Gallus gallus |
calmodulin kinase IV | - |
Gallus gallus |
CaMKIV | - |
Gallus gallus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Gallus gallus | |
Calmodulin | dependent on, 2 mM CaCl2 plus 0.001 mM calmodulin induce 69.2% activation of CaMKIV activity | Gallus gallus |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Gallus gallus | estimated from amino acid sequence | - |
8.28 |