Protein Variants | Comment | Organism |
---|---|---|
T286A | mutant clustering behaviour is similar compared to the wild type enzyme | Rattus norvegicus |
T286D | mutant mimics autophosphorylation at Thr286 | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
KN-93 | membrane permeant inhibitor of alphaCaMKII binding to Ca2+/calmodulin | Rattus norvegicus | |
additional information | not affected by myristoyl-RRKEQKTGHAVRAIGRE | Rattus norvegicus | |
myristoylated autocamtide-2-related inhibitory peptide | - |
Rattus norvegicus | |
myristoylated Trp peptide | 0.0135 mM prevents alphaCaMKII clustering | Rattus norvegicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | dependent on | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | P11275 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
hippocampus | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Thr286-autophosphorylation is antagonistic to CaMKII clustering | Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
alphaCa2+/CaM-dependent protein kinase II | - |
Rattus norvegicus |
alphaCaMKII | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Rattus norvegicus | |
Calmodulin | dependent on | Rattus norvegicus |