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Literature summary for 2.7.11.17 extracted from

  • Gangopadhyay, S.S.; Gallant, C.; Sundberg, E.J.; Lane, W.S.; Morgan, K.G.
    Regulation of Ca2+/calmodulin kinase II by a small C-terminal domain phosphatase (2008), Biochem. J., 412, 507-516.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in COS-7 and CHO cells Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoskeletal part
-
Rattus norvegicus
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ dependent on Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus P11730
-
-

Purification (Commentary)

Purification (Comment) Organism
Talon spin column chromatography and Superdex 75 gel filtration Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information CaMKIIgamma G2 autophosphorylates in the presence of Ca2+/calmodulin and ATP Rattus norvegicus ?
-
?
additional information small C-terminal domain phosphatase-3 dephosphorylates CaMKIIgamma G2, the dephosphorylation is site-specific, excluding the Thr287 associated with Ca2+/calmodulin-independent activation of the kinase, as a result the autonomous activity of CaMKIIgamma G-2 is not affected by the phosphatase activity of small C-terminal domain phosphatase-3 Rattus norvegicus ?
-
?

Synonyms

Synonyms Comment Organism
Ca2+/CaM kinase II gamma G2
-
Rattus norvegicus
CaMKIIgamma G2
-
Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
ATP
-
Rattus norvegicus
Calmodulin dependent on Rattus norvegicus