Cloned (Comment) | Organism |
---|---|
expressed in High-5 cells | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + [G-protein-coupled receptor] | Homo sapiens | GRK5 effectively phosphorylates inactive forms of several G-protein-coupled receptors, including serotonin 5-HT2C, beta2-adrenergic and M2 muscarinic receptors and rhodopsin | ADP + [G-protein-coupled receptor]phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P34947 | - |
- |
Purification (Comment) | Organism |
---|---|
Ni-NTA column chromatography | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + [G-protein-coupled receptor] | GRK5 effectively phosphorylates inactive forms of several G-protein-coupled receptors, including serotonin 5-HT2C, beta2-adrenergic and M2 muscarinic receptors and rhodopsin | Homo sapiens | ADP + [G-protein-coupled receptor]phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
G protein-coupled receptor kinase 5 | - |
Homo sapiens |
GRK5 | - |
Homo sapiens |