Cloned (Comment) | Organism |
---|---|
expression of GRK4gamma in 293T cells, which are devoid of endogenous GRK4gamma | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
K216M/K217M | a kinase-dead GRK4gamma mutant, that interacts with GalphaS and Galpha13 in the same way as the wild-type GRK4gamma | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P32298 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | GRK4 inhibits GalphaS-coupled GPCR signaling and lacks a PH domain, and GRK4gamma interacts with inactive GalphaS, inactive Gbeta, and inactive Galpha13, and to a lesser extent also with active GalphaS, subunits of heterotrimeric G proteins, overview | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
G protein-coupled receptor kinase 4gamma | - |
Homo sapiens |
GPCR kinase 4 | - |
Homo sapiens |
GRK4gamma | - |
Homo sapiens |