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Literature summary for 2.7.11.16 extracted from

  • Fraga, S.; Jose, P.A.; Soares-da-Silva, P.
    Involvement of G protein-coupled receptor kinase 4 and 6 in rapid desensitization of dopamine D1 receptor in rat IEC-6 intestinal epithelial cells (2004), Am. J. Physiol., 287, R772-779.
    View publication on PubMed
Search for more literature for 2.7.11.16

Inhibitors

Inhibitors Comment Organism Structure
heparin
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + dopamine D1 receptor Rattus norvegicus rapid desensitization of the receptor by GRK4 and GRK6, Na+/H+ exchanger activity of the receptor, overview ADP + phosphorylated dopamine D1 receptor
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
epithelium
-
 Rattus norvegicus
-
IEC-6 cell intestinal epithelial cell line Rattus norvegicus
-
small intestine
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + dopamine D1 receptor rapid desensitization of the receptor by GRK4 and GRK6, Na+/H+ exchanger activity of the receptor, overview Rattus norvegicus ADP + phosphorylated dopamine D1 receptor
-
 ?
ATP + dopamine D1 receptor GRK4 and GRK6 Rattus norvegicus ADP + phosphorylated dopamine D1 receptor
-
 ?

Synonyms

Synonyms Comment Organism
G protein-coupled receptor kinase 4
-
 Rattus norvegicus
G protein-coupled receptor kinase 6
-
 Rattus norvegicus
GRK4
-
 Rattus norvegicus
GRK6
-
 Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Rattus norvegicus