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Literature summary for 2.7.11.15 extracted from

  • Bulcao, C.F.; Pandalai, P.K.; DSouza, K.M.; Merrill, W.H.; Akhter, S.A.
    Uncoupling of myocardial beta-adrenergic receptor signaling during coronary artery bypass grafting: the role of GRK2 (2008), Ann. Thorac. Surg., 86, 1189-1194.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.11.15

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane myocardial sarcolemmal membrane Homo sapiens 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + beta-adrenergic receptor Homo sapiens the mechanism of myocardial beta-adrenergic receptor desensitization during cardiac surgery involves GRK2, overview ADP + beta-adrenergic receptor phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
heart
-
 Homo sapiens
-
myocardium myocardial G protein-coupled receptor kinase expression and activity, overview Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + beta-adrenergic receptor
-
 Homo sapiens ADP + beta-adrenergic receptor phosphate
-
 ?
ATP + beta-adrenergic receptor the mechanism of myocardial beta-adrenergic receptor desensitization during cardiac surgery involves GRK2, overview Homo sapiens ADP + beta-adrenergic receptor phosphate
-
 ?
additional information GRK2 is also active with rhodopsin, cf. EC 2.7.11.14 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
GRK2
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Homo sapiens