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Literature summary for 2.7.11.15 extracted from

  • Li, Z.; Laugwitz, K.L.; Pinkernell, K.; Pragst, I.; Baumgartner, C.; Hoffmann, E.; Rosport, K.; Munch, G.; Moretti, A.; Humrich, J.; Lohse, M.J.; Ungerer, M.
    Effects of two Gbetagamma-binding proteins - N-terminally truncated phosducin and beta-adrenergic receptor kinase C terminus (betaARKct)--in heart failure (2003), Gene Ther., 10, 1354-1361.
    View publication on PubMed
Search for more literature for 2.7.11.15

Cloned(Commentary)

Cloned (Comment) Organism
overexpression of the C-terminus of betaARK in ventricular cardiomyocytes and in the myocardium of rabbits suffering heart failure by adenoviral gene transfer, co-expression of N-terminal deletion mutant of phosducin, leading to increase in contractility of the cells due to inhibition of Gbetagamma subunits rather than to beta-adrenergic receptor resensitization, betaARK additionally stimulates cAMP production Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information construction of betaARKct mutant comprising the C-terminus of the enzyme Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens betaARK enhances the contractility in heart myocardium via inhibition of Gbetagamma subunits ?
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 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
heart
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information betaARK enhances the contractility in heart myocardium via inhibition of Gbetagamma subunits Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
betaARK
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 Homo sapiens