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Literature summary for 2.7.11.14 extracted from

  • Doza, Y.N.; Minke, B.; Chorev, M.; Selinger, Z.
    Characterization of fly rhodopsin kinase (1992), Eur. J. Biochem., 209, 1035-1040.
    View publication on PubMed
Search for more literature for 2.7.11.14

Inhibitors

Inhibitors Comment Organism Structure
arrestin competes for binding to rhodopsin Musca domestica
G-protein competes for binding to rhodopsin Musca domestica
heparin potent inhibitor Musca domestica
additional information not: protein inhibitor of cAMP-dependent protein kinase Musca domestica
Urea
-
 Musca domestica

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.009
-
 ATP pH 7.5, 20°C Musca domestica

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane membrane-bound Musca domestica 16020
-
membrane enzyme is released from rhodopsin-containing eye membranes Musca domestica 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ requirement Musca domestica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + rhodopsin Musca domestica localization of enzyme enables it to quench immediately the activated form of the photopigment ADP + phosphorhodopsin
-
 ?

Organism

Organism UniProt Comment Textmining
Musca domestica
-
 fly
-

Posttranslational Modification

Posttranslational Modification Comment Organism
additional information enzyme may be posttranslationally modified Musca domestica

Purification (Commentary)

Purification (Comment) Organism
partial, 55fold Musca domestica

Source Tissue

Source Tissue Comment Organism Textmining
eye eye-specific, not in brain or abdomen Musca domestica
-

Storage Stability

Storage Stability Organism
-70°C, at least 3 months, stable Musca domestica

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + Ac-RRRAAAAASAAA-NH2 synthetic peptide substrate Musca domestica ADP + Ac-RRRAAAAApSAAA-NH2
-
 ?
ATP + rhodopsin light-dependent phosphorylation Musca domestica ADP + phosphorhodopsin
-
 ?
ATP + rhodopsin phosphorylates rhodopsin from Musca domestica, Lucilia cuprina and Drosophila melanogaster Musca domestica ADP + phosphorhodopsin
-
 ?
ATP + rhodopsin preferred substrate: light-activated form of rhodopsin, i.e. metarhodopsin II Musca domestica ADP + phosphorhodopsin
-
 ?
ATP + rhodopsin binds tightly to its substrate metarhodopsin and partially dissociates from rhodopsin Musca domestica ADP + phosphorhodopsin
-
 ?
ATP + rhodopsin localization of enzyme enables it to quench immediately the activated form of the photopigment Musca domestica ADP + phosphorhodopsin
-
 ?
additional information almost inactive toward histone Musca domestica ?
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
20
-
 assay at Musca domestica

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 assay at Musca domestica