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Literature summary for 2.7.11.13 extracted from

  • Bowley, K.A.; Linley, J.E.; Robins, G.G.; Kopanati, S.; Hunter, M.; Sandle, G.I.
    Role of protein kinase C in aldosterone-induced non-genomic inhibition of basolateral potassium channels in human colonic crypts (2007), J. Steroid Biochem. Mol. Biol., 104, 45-52.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information no activation by 4alpha-phorbol 12-myristate 13-acetate Homo sapiens
phorbol 12-myristate 13-acetate i.e. PMA, inhibits IKCa channels Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
GΓΆ6976
-
Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the enzyme plays a role in aldosterone-induced non-genomic inhibition of basolateral potassium IKCa channels in human colonic crypts ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
colon
-
Homo sapiens
-
crypt from normal sigmoid colon Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme plays a role in aldosterone-induced non-genomic inhibition of basolateral potassium IKCa channels in human colonic crypts Homo sapiens ?
-
?

Cofactor

Cofactor Comment Organism Structure
ATP
-
Homo sapiens