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Literature summary for 2.7.11.13 extracted from

  • Eun, S.Y.; Kim, E.H.; Kang, K.S.; Kim, H.J.; Jo, S.A.; Kim, S.J.; Jo, S.H.; Kim, S.J.; Blackshear, P.J.; Kim, J.
    Cell type-specific upregulation of myristoylated alanine-rich C kinase substrate and protein kinase C-alpha, -beta I, -beta II, and -delta in microglia following kainic acid-induced seizures (2006), Exp. Mol. Med., 38, 310-319.
    View publication on PubMed
Search for more literature for 2.7.11.13

Activating Compound

Activating Compound Comment Organism Structure
Kainic acid phosphorylation of MARCKS by PKC isozymes is dramatically upregulated specifically in microglial cells after kainic acid-induced seizures, but not in other types of glial cells, overview, upregulation of isozymes PKCalpha, PKCbetaI, PKCbetaII, and PKCdelta Mus musculus

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
 Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + myristoylated alanine-rich C kinase substrate Mus musculus the substrate is involved in actincytoskeletal rearrangement in response to extra-cellular stimuli, phosphorylation of MARCKS is dramatically upregulated specifically in microglial cells after kainic acid-induced seizures, but not in other types of glial cells, overview ADP + phosphorylated myristoylated alanine-rich C kinase substrate
-
 ?
ATP + myristoylated alanine-rich C kinase substrate Mus musculus C57BL/6 the substrate is involved in actincytoskeletal rearrangement in response to extra-cellular stimuli, phosphorylation of MARCKS is dramatically upregulated specifically in microglial cells after kainic acid-induced seizures, but not in other types of glial cells, overview ADP + phosphorylated myristoylated alanine-rich C kinase substrate
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
 C57BL/6 mice
-
Mus musculus C57BL/6
-
 C57BL/6 mice
-

Source Tissue

Source Tissue Comment Organism Textmining
central nervous system
-
 Mus musculus
-
glial cell
-
 Mus musculus
-
hippocampus cellular distribution and phosphorylation of MARCKS by PKC isozymes in the hippocampus following kainic acid-induced seizures, immunohistochemic detection, overview Mus musculus
-
microglia
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + myristoylated alanine-rich C kinase substrate
-
 Mus musculus ADP + phosphorylated myristoylated alanine-rich C kinase substrate
-
 ?
ATP + myristoylated alanine-rich C kinase substrate the substrate is involved in actincytoskeletal rearrangement in response to extra-cellular stimuli, phosphorylation of MARCKS is dramatically upregulated specifically in microglial cells after kainic acid-induced seizures, but not in other types of glial cells, overview Mus musculus ADP + phosphorylated myristoylated alanine-rich C kinase substrate
-
 ?
ATP + myristoylated alanine-rich C kinase substrate
-
 Mus musculus C57BL/6 ADP + phosphorylated myristoylated alanine-rich C kinase substrate
-
 ?
ATP + myristoylated alanine-rich C kinase substrate the substrate is involved in actincytoskeletal rearrangement in response to extra-cellular stimuli, phosphorylation of MARCKS is dramatically upregulated specifically in microglial cells after kainic acid-induced seizures, but not in other types of glial cells, overview Mus musculus C57BL/6 ADP + phosphorylated myristoylated alanine-rich C kinase substrate
-
 ?

Synonyms

Synonyms Comment Organism
PKC
-
 Mus musculus

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Mus musculus