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Literature summary for 2.7.11.13 extracted from
- Calcium-independent phospholipase A2 is regulated by a novel protein kinase C in human coronary artery endothelial cells (2005), Am. J. Physiol., 288, C475-482.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| phorbol 12-myristate 13-acetate | - |
Homo sapiens |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + calcium-independent phospholipase A2 | Homo sapiens | PKC regulates membrane-associated, calcium-independent phospholipase A2 in coronary artery endothelial cells in competition to thrombin, overview | ADP + phosphorylated calcium-independent phospholipase A2 | - |
? | |
| additional information | Homo sapiens | identification of isozymes being involved in calcium-independent phospholipase A2 activation in coronary artery endothelial cells,overview | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
several isozymes | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| artery | coronary | Homo sapiens | - |
| endothelial cell | from coronary artery | Homo sapiens | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + calcium-independent phospholipase A2 | - |
Homo sapiens | ADP + phosphorylated calcium-independent phospholipase A2 | - |
? | |
| ATP + calcium-independent phospholipase A2 | PKC regulates membrane-associated, calcium-independent phospholipase A2 in coronary artery endothelial cells in competition to thrombin, overview | Homo sapiens | ADP + phosphorylated calcium-independent phospholipase A2 | - |
? | |
| additional information | identification of isozymes being involved in calcium-independent phospholipase A2 activation in coronary artery endothelial cells,overview | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PKC | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Homo sapiens | |
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Release 2023.1 (January 2023)
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