Literature summary for 2.7.11.12 extracted from

Tamura, N.; Itoh, H.; Ogawa, Y.; Nakagawa, O.; Harada, M.; Chun, T.H.; Suga, S.; Yoshimasa, T.; Nakao, K.
cDNA cloning and gene expression of human type Ialpha cGMP-dependent protein kinase (1996), Hypertension, 27, 552-557.

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Cloned(Commentary)

Cloned (Comment)	Organism
-	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	enzyme is involved in inhibition of platelet aggregation, relaxation of smooth muscle cells, and control of cardiocyte contractility. Pathophysiological implication of the type I cGK in cardiovascular diseases, including hypertension and atherosclerosis	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q13976	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	enzyme is involved in inhibition of platelet aggregation, relaxation of smooth muscle cells, and control of cardiocyte contractility. Pathophysiological implication of the type I cGK in cardiovascular diseases, including hypertension and atherosclerosis	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
CGK	-	Homo sapiens
cGMP-dependent protein kinase 1, alpha isozyme	-	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
cGMP	dependent on	Homo sapiens

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Release 2023.1 (January 2023)