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Literature summary for 2.7.11.11 extracted from
- Prazosin-stimulated release of hepatic triacylglyceride lipase from primary cultured rat hepatocytes is involved in the regulation of cAMP-dependent protein kinase through activation of the Ca(2+)/calmodulin-dependent protein kinase-II (2016), Pharmacol. Rep., 68, 649-653 .
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| KN-93 | cAMP-dependent PKA activity of prazosin-stimulated hepatocytes is suppressed | Rattus norvegicus |  |
| Trifluoperazine | cAMP-dependent PKA activity of prazosin-stimulated hepatocytes is suppressed | Rattus norvegicus | |
| U-73122 | cAMP-dependent PKA activity of prazosin-stimulated hepatocytes is suppressed | Rattus norvegicus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| hepatocyte | - |
Rattus norvegicus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| cAMP-dependent PKA | - |
Rattus norvegicus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| metabolism | prazosin-stimulated release of hepatic triacylglyceride lipase (HTGL) from hepatocytes is caused by activation of protein kinase A (PKA) associated with stimulation of Ca2+/calmodulin-dependent protein kinase II (CaMK-II) activity through a signal cascade from phospholipase C | Rattus norvegicus |
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