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Literature summary for 2.7.11.10 extracted from

  • Deng, L.; Li, Y.; Ai, P.; Xie, Y.; Zhu, H.; Chen, N.
    Increase in IkappaB kinase alpha expression suppresses the tumor progression and improves the prognosis for nasopharyngeal carcinoma (2015), Mol. Carcinog., 54, 156-165.
    View publication on PubMed
Search for more literature for 2.7.11.10

Application

Application Comment Organism
medicine enzyme expression is negatively correlated with the invasiveness, migration, and angiogenesis of nasopharyngeal carcinoma cells Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + [IkappaB protein] Homo sapiens
-
 ADP + [IkappaB phosphoprotein]
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
nasopharyngeal carcinoma cell
-
 Homo sapiens
-
NP-69-SV40T cell
-
 Homo sapiens
-
SUNE-1 cell
-
 Homo sapiens
-
SUNE-1-5-8F cell
-
 Homo sapiens
-
SUNE-1-6-10B cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + [IkappaB protein]
-
 Homo sapiens ADP + [IkappaB phosphoprotein]
-
 ?

Synonyms

Synonyms Comment Organism
IkappaB kinase alpha
-
 Homo sapiens
IKKalpha
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function the enzyme suppresses the invasion, metastasis, and angiogenesis of nasopharyngeal carcinoma cells in vitro and correlates with the survival in nasopharyngeal carcinoma patients Homo sapiens