Literature summary for 2.7.11.10 extracted from

Lin, S.T.; Wang, Y.; Xue, Y.; Feng, D.C.; Xu, Y.; Xu, L.Y.
Tetrandrine suppresses LPS-induced astrocyte activation via modulating IKKs-IkappaBalpha-NF-kappaB signaling pathway (2008), Mol. Cell. Biochem., 315, 41-49.

Search for more literature for 2.7.11.10

Application

Application	Comment	Organism
molecular biology	tetrandrine suppresses LPS-induced astrocyte activation via modulating IKKs-IkappaBalpha-NF-kappaB signaling pathway	Rattus norvegicus

Inhibitors

Inhibitors	Comment	Organism	Structure
tetrandrine	a bis-benzylisoquinoline alkaloid isolated from the roots of Han-Fang-Ji (Stephania Tetrandra S Moore) effectively inhibits IKKs phosphorylation	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
phosphoprotein	-	Rattus norvegicus

Source Tissue

Source Tissue	Comment	Organism	Textmining
astrocyte	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + IkappaBalpha	-	Rattus norvegicus	ADP + phosphorylated-IkappaBalpha	-	?

Synonyms

Synonyms	Comment	Organism
IkappaB kinase alpha	-	Rattus norvegicus
IKK	-	Rattus norvegicus

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Release 2023.1 (January 2023)