Literature summary for 2.7.10.2 extracted from

Semaan, N.; Alsaleh, G.; Gottenberg, J.E.; Wachsmann, D.; Sibilia, J.
Etk/BMX, a Btk family tyrosine kinase, and Mal contribute to the cross-talk between MyD88 and FAK pathways (2008), J. Immunol., 180, 3485-3491.

Search for more literature for 2.7.10.2

Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	phosphorylation of Etk on Y40 is required for Etk activation	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
siRNA	-	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + [protein]-L-tyrosine	Homo sapiens	-	ADP + [protein]-L-tyrosine phosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P51813	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
phosphoprotein	-	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
fibroblast-like synoviocyte	FLS	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + [protein]-L-tyrosine	-	Homo sapiens	ADP + [protein]-L-tyrosine phosphate	-	?

Synonyms

Synonyms	Comment	Organism
Bmx	-	Homo sapiens
ETK	-	Homo sapiens
Etk/BMX	-	Homo sapiens

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Release 2023.1 (January 2023)