Activating Compound | Comment | Organism | Structure |
---|---|---|---|
lysophosphatidic acid | activates fyn | Homo sapiens | |
sphingosylphosphorylcholine | activates fyn | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
expression of wild-type Fyn and mutant enzymes in murine NIH3T3 fibroblasts | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
K298M | site-directed mutagenesis, a dominant-negative enzyme mutant | Homo sapiens |
additional information | overexpression of constitutively active Fyn Y530F mutant localized at both ends of F-actin bundles triggers stress fiber formation, gene silencing of Fyn by siRNA expression or expression of dominant negative Fyn mutant K298M inhibit actin stress fiber formation in fibroblasts | Homo sapiens |
Y530F | site-directed mutagenesis, a constitutively active mutant | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
actin filament | Fyn is localized at both ends of F-actin bundles | Homo sapiens | 5884 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | Fyn tyrosine kinase is involved in actin stress fiber formation in fibroblasts | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
fibroblast | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Fyn tyrosine kinase is involved in actin stress fiber formation in fibroblasts | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Fyn tyrosine kinase | - |
Homo sapiens |