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Literature summary for 2.7.10.2 extracted from

  • McCarthy, J.V.; Ni, J.; Dixit, V.M.
    RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase (1998), J. Biol. Chem., 273, 16968-16975.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + a protein Homo sapiens NF-kappaB-activating and cell death-inducing kinase ADP + a phosphoprotein
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?
additional information Homo sapiens RIP2 interacts with members of the TNFR-1 signaling complex, including inhibitor of apoptosis protein cIAP1 and with members of the TNFR-associated factor family, specifically TRAF1, TRAF5, and TRAF6, but not with TRAF2, TRAF3, or TRAF4 ?
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?

Organism

Organism UniProt Comment Textmining
Homo sapiens O43353
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + a protein NF-kappaB-activating and cell death-inducing kinase Homo sapiens ADP + a phosphoprotein
-
?
additional information RIP2 interacts with members of the TNFR-1 signaling complex, including inhibitor of apoptosis protein cIAP1 and with members of the TNFR-associated factor family, specifically TRAF1, TRAF5, and TRAF6, but not with TRAF2, TRAF3, or TRAF4 Homo sapiens ?
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?

Synonyms

Synonyms Comment Organism
receptor-interacting serine/threonine protein kinase 2
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Homo sapiens
RIP2
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Homo sapiens