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Literature summary for 2.7.10.2 extracted from

  • Chan, A.C.; Iwashima, M.; Turck, C.W.; Weiss, A.
    ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain (1992), Cell, 71, 649-662.
    View publication on PubMed
Search for more literature for 2.7.10.2

Activating Compound

Activating Compound Comment Organism Structure
additional information tyrosine phosphorylation and association of ZAP-70 with zeta require the presence of src family PTKs Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
isolation of a cDNA clone encoding ZAP-70 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
70000
-
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens ZAP-70 that associates with T cell antigen receptor zeta chain and undergoes tyrosine phosphorylation following TCR stimulation ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P43403
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein ZAP-70 associates with T cell antigen receptor zeta chain and undergoes tyrosine phosphorylation following TCR stimulation Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
natural killer cell
-
 Homo sapiens
-
T-cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information ZAP-70 that associates with T cell antigen receptor zeta chain and undergoes tyrosine phosphorylation following TCR stimulation Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
tyrosine-protein kinase ZAP-70
-
 Homo sapiens