Application | Comment | Organism |
---|---|---|
medicine | non-oncogenic role for HER2 in the process of adipose differentiation and HER2 may represent a previously unrecognized target to manage obesity via the lipogenic enzyme FASN | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | cytoplasmic expression of HER2 significantly augments during the differentiation of preadipocytes | Mus musculus | 5737 | - |
plasma membrane | cell membrane-associated expression of HER2 significantly augments during the differentiation of preadipocytes | Mus musculus | 5886 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | P70424 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
3T3-L1 cell | HER2 is absent in undifferentiated cultures of adipocytes, not subjected to hormonal treatment but processed at the same time as the differentiating cultures from day 0 to day 14. Expression of HER2 significantly augments during the differentiation of preadipocytes. HER2 acculmulation reaches a maximum at day 9 | Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
ErbB-2 | - |
Mus musculus |
HER2 | - |
Mus musculus |
tyrosine kinase receptor HER2 | - |
Mus musculus |