Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.10.1 extracted from

  • Hunter, T.
    Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling (1995), Cell, 80, 225-236.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information one activation process in vertebrates involves activation and translocation to the plasma membrane of Ras, and/or autophosphorylation eukaryota

Inhibitors

Inhibitors Comment Organism Structure
vanadate
-
eukaryota

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane
-
eukaryota 5886
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
eukaryota

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + a protein eukaryota
-
ADP + a phosphoprotein
-
?
additional information eukaryota protein kinases and protein phosphatases regulate enzyme activities in the cell, regulation mechanisms, overview ?
-
?

Organism

Organism UniProt Comment Textmining
eukaryota
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein the enzyme is activated by autophosphorylation eukaryota

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + a protein
-
eukaryota ADP + a phosphoprotein
-
?
additional information protein kinases and protein phosphatases regulate enzyme activities in the cell, regulation mechanisms, overview eukaryota ?
-
?

Synonyms

Synonyms Comment Organism
EGF RPTK
-
eukaryota
epidermal growth factor tyrosine protein kinase
-
eukaryota
NGF RPTK
-
eukaryota
nuclear growth factor tyrosine protein kinase
-
eukaryota
platelet-derived growth factor RPTK
-
eukaryota
RPTK
-
eukaryota

Cofactor

Cofactor Comment Organism Structure
ATP
-
eukaryota