Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | one activation process in vertebrates involves activation and translocation to the plasma membrane of Ras, and/or autophosphorylation | eukaryota |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
vanadate | - |
eukaryota |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
plasma membrane | - |
eukaryota | 5886 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
eukaryota |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + a protein | eukaryota | - |
ADP + a phosphoprotein | - |
? | |
additional information | eukaryota | protein kinases and protein phosphatases regulate enzyme activities in the cell, regulation mechanisms, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
eukaryota | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | the enzyme is activated by autophosphorylation | eukaryota |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + a protein | - |
eukaryota | ADP + a phosphoprotein | - |
? | |
additional information | protein kinases and protein phosphatases regulate enzyme activities in the cell, regulation mechanisms, overview | eukaryota | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
EGF RPTK | - |
eukaryota |
epidermal growth factor tyrosine protein kinase | - |
eukaryota |
NGF RPTK | - |
eukaryota |
nuclear growth factor tyrosine protein kinase | - |
eukaryota |
platelet-derived growth factor RPTK | - |
eukaryota |
RPTK | - |
eukaryota |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
eukaryota |