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Literature summary for 2.7.10.1 extracted from

  • O'Bryan, J.P.; Frye, R.A.; Cogswell, P.C.; Neubauer, A.; Kitch, B.; Prokop, C.; Espinosa, R.; Le Beau, M.M.; Earp, H.S.; Liu, E.T.
    Axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase (1991), Mol. Cell. Biol., 11, 5016-5031.
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
overexpression of axl cDNA in NIH 3T3 cells induces neoplastic transformation with the concomitant appearance of a 140-kDa axl tyrosine-phosphorylated protein. Expression of axl cDNA in the baculovirus system results in the expression of the appropriate recombinant protein that is recognized by antiphosphotyrosine antibodies Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P30530 patients with chronic myelogenous leukemia
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Source Tissue

Source Tissue Comment Organism Textmining
myeloid leukemia cell
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 Homo sapiens
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Synonyms

Synonyms Comment Organism
tyrosine-protein kinase receptor UFO
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 Homo sapiens