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Literature summary for 2.7.1.91 extracted from

  • Guo, Q.; Li, Q.; Liu, H.; Li, R.; Wu, C.; Wang, L.
    Sphingosine kinase 1 gene transfer reduces postoperative peritoneal adhesion in an experimental model (2008), Br. J. Surg., 95, 252-258.
    View publication on PubMed

Application

Application Comment Organism
medicine adenovirus-mediated SPK1 gene transfer promotes recovery of the surgically damaged mesothelial cell layer and prevents postoperative peritoneal adhesion formation Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
mesothelium
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Homo sapiens
-

General Information

General Information Comment Organism
physiological function adenovirus-mediated SPK1 gene transfer to rat mesothelial cells increases the cellular SPK1 activity, and leads to enhanced migration. Median adhesion scores are significantly lower in the transfected group than in controls in both rat caecum and rat uterine horn models Homo sapiens