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Literature summary for 2.7.1.91 extracted from
- Extracellular nucleotides induce migration of renal mesangial cells by upregulating sphingosine kinase-1 expression and activity (2007), Br. J. Pharmacol., 150, 271-280.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| K+ | 1 mM | Rattus norvegicus |  |
| additional information | not inhibited by K+ | Rattus norvegicus |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 49000 | - |
SDS-PAGE | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | Q6AYB2 | - |
- |
| Rattus norvegicus | Q91V26 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| mesangial cell | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + sphingosine | - |
Rattus norvegicus | ADP + sphingosine 1-phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| SK-1 | - |
Rattus norvegicus |
| SK-2 | - |
Rattus norvegicus |
| sphingosine kinase-1 | - |
Rattus norvegicus |
| sphingosine kinase-2 | - |
Rattus norvegicus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Rattus norvegicus | |
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Release 2023.1 (January 2023)
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