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Literature summary for 2.7.1.86 extracted from

  • Panagiotou, G.; Grotkjaer, T.; Hofmann, G.; Bapat, P.M.; Olsson, L.
    Overexpression of a novel endogenous NADH kinase in Aspergillus nidulans enhances growth (2008), Metab. Eng., 11, 31-39.
    View publication on PubMed
Search for more literature for 2.7.1.86

Cloned(Commentary)

Cloned (Comment) Organism
overexpressed in Aspergillus AR1 derived from the natural isolate A4, pTr04 expression vector Aspergillus nidulans

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
49000
-
 predicted Aspergillus nidulans

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + NAD+ Aspergillus nidulans
-
 ADP + NADP+
-
 ?
ATP + NAD+ Aspergillus nidulans CBS 513.88 / FGSC A1513
-
 ADP + NADP+
-
 ?

Organism

Organism UniProt Comment Textmining
Aspergillus nidulans
-
-
-
Aspergillus nidulans CBS 513.88 / FGSC A1513
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 gene encoding NADH kinase identified, overexpression using constitutive promoter, physiologcal effects in combination with different aeration rates in glucose batch fermentation, metabolite profiling, relative amounts of intracellular amino and non-amino organic acids compared, enzyme activity significantly correlated with growth activity Aspergillus nidulans

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + NAD+
-
 Aspergillus nidulans ADP + NADP+
-
 ?
ATP + NAD+ phenotypic effects during overexpression analyzed by simulation of major metabolic fluxes Aspergillus nidulans ADP + NADP+
-
 ?
ATP + NAD+
-
 Aspergillus nidulans CBS 513.88 / FGSC A1513 ADP + NADP+
-
 ?
ATP + NAD+ phenotypic effects during overexpression analyzed by simulation of major metabolic fluxes Aspergillus nidulans CBS 513.88 / FGSC A1513 ADP + NADP+
-
 ?

Synonyms

Synonyms Comment Organism
NADH kinase
-
 Aspergillus nidulans