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Literature summary for 2.7.1.86 extracted from

  • Strand, M.K.; Stuart, G.R.; Longley, M.J.; Graziewicz, M.A.; Dominick, O.C.; Copeland, W.C.
    POS5 gene of Saccharomyces cerevisiae encodes a mitochondrial NADH kinase required for stability of mitochondrial DNA (2003), Eukaryot. Cell, 2, 809-820.
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
overproduction of the POS5 gene product in Escherichia coli Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion enzyme functions exclusively in mitochondria Saccharomyces cerevisiae 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Saccharomyces cerevisiae POS5 NADH kinase is required for mitochondrial stability with a critical role in detoxification of reactive oxygen species ?
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 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
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-
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Purification (Commentary)

Purification (Comment) Organism
-
 Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + NAD+ 2fold preference for NADH over NAD+ Saccharomyces cerevisiae ADP + NADP+
-
 ?
ATP + NADH 2fold preference for NADH over NAD+ Saccharomyces cerevisiae ADP + NADPH
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 ?
additional information POS5 NADH kinase is required for mitochondrial stability with a critical role in detoxification of reactive oxygen species Saccharomyces cerevisiae ?
-
 ?