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Literature summary for 2.7.1.78 extracted from
- Characterization of the 2,3 cyclic phosphodiesterase activities of Clostridium thermocellum polynucleotide kinase-phosphatase and bacteriophage lambda phosphatase (2007), Nucleic Acids Res., 35, 7721-7732.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| H189D | mutation transforms enzyme into a Mn2+-dependent phosphodiesterase devoid of monoesterase activity. Phosphodiesterase activity of mutant is strictly specific for 2',3'-cyclic phosphates which it hydrolyzes to yield a 2'-NMP as the sole product | Acetivibrio thermocellus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Acetivibrio thermocellus | - |
bifunctional polynucleotide kinase/2',3'-cyclic nucleotide phosphodiesterase | - |
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Release 2023.1 (January 2023)
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