BRENDA - Enzyme Database show
show all sequences of 2.7.1.76

Structure-function analysis of a bacterial deoxyadenosine kinase reveals the basis for substrate specificity

Welin, M.; Wang, L.; Eriksson, S.; Eklund, H.; J. Mol. Biol. 366, 1615-1623 (2007)

Data extracted from this reference:

Crystallization (Commentary)
Crystallization
Organism
in complex with deoxyadenosine 5'-triphosphate and 2'-deoxycytidine 5'-triphosphate, as well as with products 2'-deoxycytidine 5'-phosphate and 2'-deoxycytidine 5'-diphosphate. Both deoxyadenosine 5'-triphosphate and 2'-deoxycytidine 5'-triphosphate bind to the enzyme in a feedback-inhibitory manner with the deoxyribonucleoside part in the deoxyribonucleoside binding site and the triphosphates in the P-loop. Superposition with human counterparts deoxyguanosine kinase and deoxycytidine kinase. Overall structures are very similar with a few amino acid alterations in the proximity of the active site; sitting drop vapour diffusion method using 24% (w/v) PEG 3350 and 0.2 M KSCN
Mycoplasma mycoides
Inhibitors
Inhibitors
Commentary
Organism
Structure
dATP
feedback inhibitor
Mycoplasma mycoides
dCTP
feedback inhibitor
Mycoplasma mycoides
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
25000
-
2 * 25000, Superdex 75 column gel filtration
Mycoplasma mycoides
50000
-
Superdex 75 column gel filtration
Mycoplasma mycoides
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Mycoplasma mycoides
-
subspecies Mycoplasma mycoides mycoides
-
Mycoplasma mycoides
Q93IG4
-
-
Purification (Commentary)
Commentary
Organism
Superdex 75 column gel filtration
Mycoplasma mycoides
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ATP + 1-beta-D-arabinofuranosyl cytosine
3% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + 1-beta-D-arabinofuranosyl cytosine 5'-phosphate
-
-
-
?
ATP + 1-beta-D-arabinofuranosyl cytosine
3% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 1-beta-D-arabinofuranosyl cytosine 5'-phosphate
-
-
-
?
ATP + 1-beta-D-arabinofuranosyl uracil
0.3% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 1-beta-D-arabinofuranosyl uracil 5'-phosphate
-
-
-
?
ATP + 2',2'-difluoro-2'-deoxycytidine
20% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2',2'-difluoro-2'-deoxycytidine monophosphate
-
-
-
?
ATP + 2',2'-difluoro-2'-deoxycytidine
20% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2',2'-difluoro-2'-deoxycytidine 5'-phosphate
-
-
-
?
ATP + 2',2'-difluoro-2'-deoxyguanosine
24% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2',2'-difluoro-2'-deoxyguanosine monophosphate
-
-
-
?
ATP + 2',2'-difluoro-2'-deoxyguanosine
24% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2',2'-difluoro-2'-deoxyguanosine 5'-phosphate
-
-
-
?
ATP + 2',3'-dideoxyadenosine
1.5% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2',3'-dideoxyadenosine monophosphate
-
-
-
?
ATP + 2',3'-dideoxyadenosine
1.5% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2',3'-dideoxyadenosine 5'-monophosphate
-
-
-
?
ATP + 2',3'-dideoxycytidine
0.1% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2',3'-dideoxycytidine 5'-monophosphate
-
-
-
?
ATP + 2',3'-dideoxyguanosine
0.5% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2',3'-dideoxyguanosine 5'-monophosphate
-
-
-
?
ATP + 2',3'-dideoxyinoosine
3.9% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2',3'-dideoxyinosine 5'-monophosphate
-
-
-
?
ATP + 2',3'-dideoxyinosine
3.9% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2',3'-dideoxyinosine 5'-phosphate
-
-
-
?
ATP + 2'-deoxyadenosine
-
675428
Mycoplasma mycoides
ADP + 2'-deoxyadenosine 5'-phosphate
-
-
-
?
ATP + 2'-deoxycytidine
81% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2'-deoxycytidine 5'-phosphate
-
-
-
?
ATP + 2'-deoxyguanosine
97% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2'-deoxyguanosine 5'-phosphate
-
-
-
?
ATP + 2'-deoxyinosine
116% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2'-deoxyinosine 5'-phosphate
-
-
-
?
ATP + 2'-deoxythymidine
0.01% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2'-deoxythymidine 5'-phosphate
-
-
-
?
ATP + 2'-deoxyuridine
0.9% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2'-deoxyuridine 5'-phosphate
-
-
-
?
ATP + 2'-fluoro-arabinosyl adenine
15% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2'-fluoro-arabinosyl adenine monophosphate
-
-
-
?
ATP + 2'-fluoro-arabinosyl adenine
15% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2'-fluoro-arabinosyl adenine 5'-monophosphate
-
-
-
?
ATP + 2-chloro-2'-deoxyadenosine
111% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2-chloro-2'-deoxyadenosine monophosphate
-
-
-
?
ATP + 2-chloro-2'-deoxyadenosine
111% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2-chloro-2'-deoxyadenosine 5'-phosphate
-
-
-
?
ATP + 9-beta-D-arabinofuranosyl adenine
77% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + 9-beta-D-arabinofuranosyl adenine 5'-monophosphate
-
-
-
?
ATP + 9-beta-D-arabinofuranosyl adenine
77% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 9-beta-D-arabinofuranosyl adenine 5'-phosphate
-
-
-
?
ATP + 9-beta-D-arabinofuranosyl guanine
6% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + 9-beta-D-arabinofuranosyl guanine 5'-monophosphate
-
-
-
?
ATP + 9-beta-D-arabinofuranosyl guanine
6% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 9-beta-D-arabinofuranosyl guanine 5'-phosphate
-
-
-
?
ATP + adenosine
7.4% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + AMP
-
-
-
?
ATP + adenosine
7.4% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + adenosine 5'-monophosphate
-
-
-
?
ATP + cytidine
0.1% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + cytidine 5'-monophosphate
-
-
-
?
ATP + deoxyadenosine
100% activity
675428
Mycoplasma mycoides
ADP + dAMP
-
-
-
?
ATP + deoxycytosine
81% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + dCMP
-
-
-
?
ATP + deoxyguanosine
97% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + dGMP
-
-
-
?
ATP + deoxyinosine
116% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + dIMP
-
-
-
?
ATP + deoxyuridine
0.9% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + dUMP
-
-
-
?
ATP + guanosine
5.5% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + GMP
-
-
-
?
ATP + guanosine
5.5% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + guanosine 5'-monophosphate
-
-
-
?
ATP + inosine
5.9% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + IMP
-
-
-
?
ATP + inosine
5.9% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + inosine monophosphate
-
-
-
?
ATP + penciclovir
1.4% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + ?
-
-
-
?
CTP + deoxyadenosine
57% activity compared to ATP
675428
Mycoplasma mycoides
CDP + dAMP
-
-
-
?
dATP + deoxyadenosine
2% activity compared to ATP
675428
Mycoplasma mycoides
dADP + dAMP
-
-
-
?
dCTP + deoxyadenosine
106% activity compared to ATP
675428
Mycoplasma mycoides
dCDP + dAMP
-
-
-
?
dTTP + deoxyadenosine
44% activity compared to ATP
675428
Mycoplasma mycoides
dTDP + dAMP
-
-
-
?
additional information
less than 1% activity with dGTP, deoxyuridine, deoxythymidine, 1-beta-D-arabinofuranosyl uracil, 2',3'-dideoxyguanosine, 2',3'-dideoxycytidine, cytidine, acyclovir, ganciclovir, 2'-deoxy-2'-fluoro-1-beta-D-arabinofuranosyl-5-iodouracil, and 5-fluoro-2'-deoxyuridine
675428
Mycoplasma mycoides
?
-
-
-
-
UTP + deoxyadenosine
22% activity compared to ATP
675428
Mycoplasma mycoides
UDP + dAMP
-
-
-
?
Subunits
Subunits
Commentary
Organism
dimer
2 * 25000, Superdex 75 column gel filtration
Mycoplasma mycoides
Cofactor
Cofactor
Commentary
Organism
Structure
ATP
-
Mycoplasma mycoides
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
ATP
-
Mycoplasma mycoides
Crystallization (Commentary) (protein specific)
Crystallization
Organism
in complex with deoxyadenosine 5'-triphosphate and 2'-deoxycytidine 5'-triphosphate, as well as with products 2'-deoxycytidine 5'-phosphate and 2'-deoxycytidine 5'-diphosphate. Both deoxyadenosine 5'-triphosphate and 2'-deoxycytidine 5'-triphosphate bind to the enzyme in a feedback-inhibitory manner with the deoxyribonucleoside part in the deoxyribonucleoside binding site and the triphosphates in the P-loop. Superposition with human counterparts deoxyguanosine kinase and deoxycytidine kinase. Overall structures are very similar with a few amino acid alterations in the proximity of the active site
Mycoplasma mycoides
sitting drop vapour diffusion method using 24% (w/v) PEG 3350 and 0.2 M KSCN
Mycoplasma mycoides
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
dATP
feedback inhibitor
Mycoplasma mycoides
dCTP
feedback inhibitor
Mycoplasma mycoides
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
25000
-
2 * 25000, Superdex 75 column gel filtration
Mycoplasma mycoides
50000
-
Superdex 75 column gel filtration
Mycoplasma mycoides
Purification (Commentary) (protein specific)
Commentary
Organism
Superdex 75 column gel filtration
Mycoplasma mycoides
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ATP + 1-beta-D-arabinofuranosyl cytosine
3% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + 1-beta-D-arabinofuranosyl cytosine 5'-phosphate
-
-
-
?
ATP + 1-beta-D-arabinofuranosyl cytosine
3% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 1-beta-D-arabinofuranosyl cytosine 5'-phosphate
-
-
-
?
ATP + 1-beta-D-arabinofuranosyl uracil
0.3% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 1-beta-D-arabinofuranosyl uracil 5'-phosphate
-
-
-
?
ATP + 2',2'-difluoro-2'-deoxycytidine
20% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2',2'-difluoro-2'-deoxycytidine monophosphate
-
-
-
?
ATP + 2',2'-difluoro-2'-deoxycytidine
20% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2',2'-difluoro-2'-deoxycytidine 5'-phosphate
-
-
-
?
ATP + 2',2'-difluoro-2'-deoxyguanosine
24% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2',2'-difluoro-2'-deoxyguanosine monophosphate
-
-
-
?
ATP + 2',2'-difluoro-2'-deoxyguanosine
24% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2',2'-difluoro-2'-deoxyguanosine 5'-phosphate
-
-
-
?
ATP + 2',3'-dideoxyadenosine
1.5% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2',3'-dideoxyadenosine monophosphate
-
-
-
?
ATP + 2',3'-dideoxyadenosine
1.5% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2',3'-dideoxyadenosine 5'-monophosphate
-
-
-
?
ATP + 2',3'-dideoxycytidine
0.1% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2',3'-dideoxycytidine 5'-monophosphate
-
-
-
?
ATP + 2',3'-dideoxyguanosine
0.5% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2',3'-dideoxyguanosine 5'-monophosphate
-
-
-
?
ATP + 2',3'-dideoxyinoosine
3.9% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2',3'-dideoxyinosine 5'-monophosphate
-
-
-
?
ATP + 2',3'-dideoxyinosine
3.9% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2',3'-dideoxyinosine 5'-phosphate
-
-
-
?
ATP + 2'-deoxyadenosine
-
675428
Mycoplasma mycoides
ADP + 2'-deoxyadenosine 5'-phosphate
-
-
-
?
ATP + 2'-deoxycytidine
81% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2'-deoxycytidine 5'-phosphate
-
-
-
?
ATP + 2'-deoxyguanosine
97% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2'-deoxyguanosine 5'-phosphate
-
-
-
?
ATP + 2'-deoxyinosine
116% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2'-deoxyinosine 5'-phosphate
-
-
-
?
ATP + 2'-deoxythymidine
0.01% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2'-deoxythymidine 5'-phosphate
-
-
-
?
ATP + 2'-deoxyuridine
0.9% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2'-deoxyuridine 5'-phosphate
-
-
-
?
ATP + 2'-fluoro-arabinosyl adenine
15% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2'-fluoro-arabinosyl adenine monophosphate
-
-
-
?
ATP + 2'-fluoro-arabinosyl adenine
15% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2'-fluoro-arabinosyl adenine 5'-monophosphate
-
-
-
?
ATP + 2-chloro-2'-deoxyadenosine
111% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2-chloro-2'-deoxyadenosine monophosphate
-
-
-
?
ATP + 2-chloro-2'-deoxyadenosine
111% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 2-chloro-2'-deoxyadenosine 5'-phosphate
-
-
-
?
ATP + 9-beta-D-arabinofuranosyl adenine
77% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + 9-beta-D-arabinofuranosyl adenine 5'-monophosphate
-
-
-
?
ATP + 9-beta-D-arabinofuranosyl adenine
77% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 9-beta-D-arabinofuranosyl adenine 5'-phosphate
-
-
-
?
ATP + 9-beta-D-arabinofuranosyl guanine
6% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + 9-beta-D-arabinofuranosyl guanine 5'-monophosphate
-
-
-
?
ATP + 9-beta-D-arabinofuranosyl guanine
6% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + 9-beta-D-arabinofuranosyl guanine 5'-phosphate
-
-
-
?
ATP + adenosine
7.4% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + AMP
-
-
-
?
ATP + adenosine
7.4% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + adenosine 5'-monophosphate
-
-
-
?
ATP + cytidine
0.1% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + cytidine 5'-monophosphate
-
-
-
?
ATP + deoxyadenosine
100% activity
675428
Mycoplasma mycoides
ADP + dAMP
-
-
-
?
ATP + deoxycytosine
81% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + dCMP
-
-
-
?
ATP + deoxyguanosine
97% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + dGMP
-
-
-
?
ATP + deoxyinosine
116% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + dIMP
-
-
-
?
ATP + deoxyuridine
0.9% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + dUMP
-
-
-
?
ATP + guanosine
5.5% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + GMP
-
-
-
?
ATP + guanosine
5.5% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + guanosine 5'-monophosphate
-
-
-
?
ATP + inosine
5.9% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + IMP
-
-
-
?
ATP + inosine
5.9% of the activity with 2'-deoxyadenosine
675428
Mycoplasma mycoides
ADP + inosine monophosphate
-
-
-
?
ATP + penciclovir
1.4% relative activity compared to deoxyadenosine
675428
Mycoplasma mycoides
ADP + ?
-
-
-
?
CTP + deoxyadenosine
57% activity compared to ATP
675428
Mycoplasma mycoides
CDP + dAMP
-
-
-
?
dATP + deoxyadenosine
2% activity compared to ATP
675428
Mycoplasma mycoides
dADP + dAMP
-
-
-
?
dCTP + deoxyadenosine
106% activity compared to ATP
675428
Mycoplasma mycoides
dCDP + dAMP
-
-
-
?
dTTP + deoxyadenosine
44% activity compared to ATP
675428
Mycoplasma mycoides
dTDP + dAMP
-
-
-
?
additional information
less than 1% activity with dGTP, deoxyuridine, deoxythymidine, 1-beta-D-arabinofuranosyl uracil, 2',3'-dideoxyguanosine, 2',3'-dideoxycytidine, cytidine, acyclovir, ganciclovir, 2'-deoxy-2'-fluoro-1-beta-D-arabinofuranosyl-5-iodouracil, and 5-fluoro-2'-deoxyuridine
675428
Mycoplasma mycoides
?
-
-
-
-
UTP + deoxyadenosine
22% activity compared to ATP
675428
Mycoplasma mycoides
UDP + dAMP
-
-
-
?
Subunits (protein specific)
Subunits
Commentary
Organism
dimer
2 * 25000, Superdex 75 column gel filtration
Mycoplasma mycoides
Other publictions for EC 2.7.1.76
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
739204
Clausen
Plants salvage deoxyribonucleo ...
Arabidopsis thaliana, Solanum tuberosum
Nucleosides Nucleotides Nucleic Acids
33
291-295
2014
-
-
-
-
-
-
-
-
2
-
-
2
-
6
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
2
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
694483
Joachims
Inhibition of deoxynucleoside ...
Homo sapiens
Nucleosides Nucleotides Nucleic Acids
27
816-820
2008
-
1
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
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