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Literature summary for 2.7.1.74 extracted from

  • Degwert, N.; Latuske, E.; Vohwinkel, G.; Stamm, H.; Klokow, M.; Bokemeyer, C.; Fiedler, W.; Wellbrock, J.
    Deoxycytidine kinase is downregulated under hypoxic conditions and confers resistance against cytarabine in acute myeloid leukaemia (2016), Eur. J. Haematol., 97, 239-244 .
    View publication on PubMed
Search for more literature for 2.7.1.74

Organism

Organism UniProt Comment Textmining
Homo sapiens P27707
-
-

Source Tissue

Source Tissue Comment Organism Textmining
acute myeloid leukemia cell
-
 Homo sapiens
-
HL-60 cell
-
 Homo sapiens
-
Kasumi-1 cell
-
 Homo sapiens
-
KG-1 cell
-
 Homo sapiens
-
MOLM-13 cell
-
 Homo sapiens
-
MV-4-11 cell
-
 Homo sapiens
-
OCI-AML5 cell
-
 Homo sapiens
-
OCI-M1 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
NTP + cytarabine
-
 Homo sapiens NDP + cytarabine 5'-phosphate
-
 ?

Synonyms

Synonyms Comment Organism
dCK
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens the enzyme is downregulated under hypoxic conditions down

General Information

General Information Comment Organism
physiological function the enzyme confers resistance against cytarabine in acute myeloid leukaemia Homo sapiens