Literature summary for 2.7.1.74 extracted from
Shafiee, M.; Gosselin, G.; Imbach, J.L.; Divita, G.; Eriksson, S.; Maury, G.
Study of human deoxycytidine kinase binding properties using intrinsic fluorescence or new fluorescent ligands (1999), Eur. J. Med. Chem., 34, 423-431.
No PubMed abstract available
Activating Compound
Activating Compound |
Comment |
Organism |
Structure |
NaF |
15 mM, 1 h, activity about twice as high as initial level |
Homo sapiens |
|
KM Value [mM]
KM Value [mM] |
KM Value Maximum [mM] |
Substrate |
Comment |
Organism |
Structure |
additional information |
- |
additional information |
Km-values of D-and L-analogues of cytidine and adenosine |
Homo sapiens |
|
Organism
Organism |
UniProt |
Comment |
Textmining |
Homo sapiens |
- |
- |
- |
Reaction
Reaction |
Comment |
Organism |
Reaction ID |
NTP + deoxycytidine = NDP + dCMP |
mechanism |
Homo sapiens |
|
Renatured (Commentary)
Renatured (Comment) |
Organism |
after elution from Sephadex column, reactivation by incubation with 50 mM dithiothreitol and 1 mg/ml bovine serum albumin |
Homo sapiens |
Source Tissue
Source Tissue |
Comment |
Organism |
Textmining |
lymphocyte |
tonsillar lymphocyte |
Homo sapiens |
- |
Substrates and Products (Substrate)
Substrates |
Comment Substrates |
Organism |
Products |
Comment (Products) |
Rev. |
Reac. |
additional information |
lack of enantioselectivity for D- and L-analogues of cytidine and adenosine |
Homo sapiens |
? |
- |
? |
|