Any feedback?
Literature summary for 2.7.1.74 extracted from
- Deoxynucleoside phosphorylating enzymes in monkey and human tissues show great similarities, while mouse deoxycytidine kinase has a different substrate specificity (1991), Biochem. Pharmacol., 42, 1829-1836.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Mus musculus | 5829 | - |
| cytosol | - |
Homo sapiens | 5829 | - |
| cytosol | - |
Aotus trivirgatus | 5829 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 30000 | - |
2 * 30000, SDS-PAGE | Mus musculus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + deoxycytidine | Mus musculus | key enzyme in anabolic phosphorylation of deoxyribonucleosides and their analogues | ADP + ? | - |
? |  |
| ATP + deoxycytidine | Homo sapiens | key enzyme in anabolic phosphorylation of deoxyribonucleosides and their analogues | ADP + ? | - |
? | |
| ATP + deoxycytidine | Aotus trivirgatus | key enzyme in anabolic phosphorylation of deoxyribonucleosides and their analogues | ADP + ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Aotus trivirgatus | - |
- |
- |
| Homo sapiens | - |
- |
- |
| Mus musculus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| spleen | Mus musculus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Mus musculus | - |
| liver | - |
Homo sapiens | - |
| liver | - |
Aotus trivirgatus | - |
| spleen | - |
Mus musculus | - |
| spleen | - |
Homo sapiens | - |
| spleen | - |
Aotus trivirgatus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + deoxycytidine | key enzyme in anabolic phosphorylation of deoxyribonucleosides and their analogues | Mus musculus | ADP + ? | - |
? | |
| ATP + deoxycytidine | key enzyme in anabolic phosphorylation of deoxyribonucleosides and their analogues | Homo sapiens | ADP + ? | - |
? | |
| ATP + deoxycytidine | key enzyme in anabolic phosphorylation of deoxyribonucleosides and their analogues | Aotus trivirgatus | ADP + ? | - |
? | |
| NTP + 2',3'-dideoxycytidine | poor | Mus musculus | NDP + 2',3'-dideoxycytidine 5'-phosphate | - |
? | |
| NTP + deoxyadenosine | - |
Homo sapiens | NDP + dAMP | - |
? | |
| NTP + deoxyadenosine | - |
Aotus trivirgatus | NDP + dAMP | - |
? | |
| NTP + deoxyadenosine | poor | Mus musculus | NDP + dAMP | - |
? | |
| NTP + deoxycytidine | - |
Mus musculus | NDP + dCMP | - |
? | |
| NTP + deoxycytidine | - |
Homo sapiens | NDP + dCMP | - |
? | |
| NTP + deoxycytidine | - |
Aotus trivirgatus | NDP + dCMP | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | - |
Homo sapiens |
| dimer | 2 * 30000, SDS-PAGE | Mus musculus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
