Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Phospholipid cofactor | phospholipid cofactor required | Staphylococcus aureus |
General Stability | Organism |
---|---|
remarkably stable towards SDS, 8 M urea and SH-reagents | Staphylococcus aureus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
guanidine hydrochloride | - |
Staphylococcus aureus | |
NaCl | above 0.5 M | Staphylococcus aureus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.057 | - |
ATP | - |
Staphylococcus aureus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Staphylococcus aureus | 16020 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
NaCl | 0.5 M, stimulates about 2-fold | Staphylococcus aureus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
17000 | - |
apoprotein, gel filtration | Staphylococcus aureus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Staphylococcus aureus | the product of the reaction, C55-isoprenoid alcohol monophosphate functions in the biosynthesis of bacterial peptidoglycan and lipopolysaccharides | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Staphylococcus aureus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
lipoprotein | phospholipid cofactor required | Staphylococcus aureus |
Purification (Comment) | Organism |
---|---|
- |
Staphylococcus aureus |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Staphylococcus aureus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + C55-isoprenoid alcohol | - |
Staphylococcus aureus | ADP + C55-isoprenoid alcohol monophosphate | - |
? | |
ATP + ficaprenol | - |
Staphylococcus aureus | ADP + ficaprenyl phosphate | - |
? | |
ATP + solanesol | poor substrate | Staphylococcus aureus | ADP + solanesyl phosphate | - |
? | |
additional information | the product of the reaction, C55-isoprenoid alcohol monophosphate functions in the biosynthesis of bacterial peptidoglycan and lipopolysaccharides | Staphylococcus aureus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 17000, SDS-PAGE | Staphylococcus aureus |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
100 | - |
30 min, about 30% loss of activity | Staphylococcus aureus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.5 | - |
- |
Staphylococcus aureus |