General Stability | Organism |
---|---|
relatively unstable in suspension in water | Staphylococcus aureus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Mn2+ | complete inhibition at 0.01 M | Staphylococcus aureus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.4 | - |
ATP | pH 8.2, 37°C, reaction with ficaprenol | Staphylococcus aureus | |
0.5 | - |
ficaprenol | pH 8.2, 37°C | Staphylococcus aureus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | exclusively found in the cell membrane fraction | Staphylococcus aureus | 16020 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Co2+ | no effect | Staphylococcus aureus | |
Mg2+ | optimum concentration: 0.01 M | Staphylococcus aureus | |
Mg2+ | divalent cation required, Mg2+ most effective, optimal concentration: 0.01 M | Staphylococcus aureus | |
Mn2+ | can partially replace Mg2+ in activation | Staphylococcus aureus | |
Mn2+ | one-fourth of the activity of Mg2+ at 0.001 M | Staphylococcus aureus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Staphylococcus aureus | product of the reaction is a substrate for the synthesis of lipid intermediates in peptidoglycan synthesis | ? | - |
? |
Organic Solvent | Comment | Organism |
---|---|---|
1-butanol | highly stable | Staphylococcus aureus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Staphylococcus aureus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + ficaprenol | - |
Staphylococcus aureus | ADP + ficaprenyl phosphate | - |
? | |
ATP + solanesol | no activity | Staphylococcus aureus | ADP + solanesyl phosphate | - |
? | |
additional information | product of the reaction is a substrate for the synthesis of lipid intermediates in peptidoglycan synthesis | Staphylococcus aureus | ? | - |
? |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
100 | - |
pH 8.2, aqueous suspension in Tris-HCl, presence of substrate, t1/2: 10 min | Staphylococcus aureus |
100 | - |
solution in 1-butanol, activation of nearly 50% after 20 min | Staphylococcus aureus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.2 | - |
- |
Staphylococcus aureus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
7.2 | 8.8 | pH 7.2: about 80% of maximal activity, pH 8.8: about 70% of maximal activity | Staphylococcus aureus |