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Literature summary for 2.7.1.60 extracted from

  • Ghaderi, D.; Strauss, H.M.; Reinke, S.; Cirak, S.; Reutter, W.; Lucka, L.; Hinderlich, S.
    Evidence for dynamic interplay of different oligomeric states of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase by biophysical methods (2007), J. Mol. Biol., 369, 746-758.
    View publication on PubMed
Search for more literature for 2.7.1.60

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Sf-9 cells Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Rattus norvegicus 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
83500
-
 4 * 83500, dynamic light scattering, the tetramer likely represents the active state of the enzyme in the cell Rattus norvegicus
85000
-
 4 * 85000, gel filtration Rattus norvegicus
334000
-
 dynamic light scattering Rattus norvegicus
340000
-
 gel filtration Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
MonoQ HR 5/5 column chromatography, PD-10 column chromatography, and Superdex 200 gel filtration Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + N-acetyl-D-mannosamine
-
 Rattus norvegicus ADP + N-acetyl-D-mannosamine 6-phosphate
-
 ?

Subunits

Subunits Comment Organism
tetramer 4 * 83500, dynamic light scattering, the tetramer likely represents the active state of the enzyme in the cell Rattus norvegicus
tetramer 4 * 85000, gel filtration Rattus norvegicus

Synonyms

Synonyms Comment Organism
GNE
-
 Rattus norvegicus
UDP-GlcNAc-epimerase/ManNAc kinase
-
 Rattus norvegicus
UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase
-
 Rattus norvegicus