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Literature summary for 2.7.1.6 extracted from
- Discovery of novel inhibitors of human galactokinase by virtual screening (2019), J. Comput. Aided Mol. Des., 33, 405-417 .
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | discovery of novel inhibitors of human galactokinase by high-throughput structure-based virtual screening | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + alpha-D-galactose | Homo sapiens | - |
ADP + alpha-D-galactose 1-phosphate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P51570 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + alpha-D-galactose | - |
Homo sapiens | ADP + alpha-D-galactose 1-phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| GALK1 | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| drug target | a pharmacological inhibitor of galactokinase is hypothesized to be therapeutic strategy for treating galactosemia by reducing production of alpha-D-galactose 1-phosphate | Homo sapiens |
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