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Literature summary for 2.7.1.6 extracted from

  • Zhang, X.; Sheng, W.; Li, K.; Rong, Y.; Wu, Q.; Meng, Q.; Kong, Y.; Chen, M.
    Substrate specificity of the galactokinase from the human gut symbiont Akkermansia muciniphila ATCC BAA-835 (2020), Enzyme Microb. Technol., 139, 109568 .
    View publication on PubMed
Search for more literature for 2.7.1.6

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Akkermansia muciniphila

Inhibitors

Inhibitors Comment Organism Structure
EDTA
-
 Akkermansia muciniphila

Metals/Ions

Metals/Ions Comment Organism Structure
Ba2+ 10 mM, slight activation Akkermansia muciniphila
Ca2+ 10 mM, slight activation Akkermansia muciniphila
Mg2+ 10 mM, the enzyme requires Mg2+ Akkermansia muciniphila
Ni2+ 10 mM, slight activation Akkermansia muciniphila

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + alpha-D-galactose Akkermansia muciniphila
-
 ADP + alpha-D-galactose 1-phosphate
-
 ?
ATP + alpha-D-galactose Akkermansia muciniphila ATCC BAA-835
-
 ADP + alpha-D-galactose 1-phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Akkermansia muciniphila B2UQR6
-
-
Akkermansia muciniphila ATCC BAA-835 B2UQR6
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Akkermansia muciniphila

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + alpha-D-galactose
-
 Akkermansia muciniphila ADP + alpha-D-galactose 1-phosphate
-
 ?
ATP + alpha-D-galactose
-
 Akkermansia muciniphila ATCC BAA-835 ADP + alpha-D-galactose 1-phosphate
-
 ?
ATP + D-galactosamine 100% of the activity with alpha-D-galactose Akkermansia muciniphila ADP + D-galactosamine 1-phosphate
-
 ?
ATP + D-galactosamine 100% of the activity with alpha-D-galactose Akkermansia muciniphila ATCC BAA-835 ADP + D-galactosamine 1-phosphate
-
 ?
ATP + D-galacturonic acid 20.2% of the activity with alpha-D-galactose Akkermansia muciniphila ADP + D-galacturonic acid 1-phosphate
-
 ?
ATP + D-galacturonic acid 20.2% of the activity with alpha-D-galactose Akkermansia muciniphila ATCC BAA-835 ADP + D-galacturonic acid 1-phosphate
-
 ?
ATP + D-glucose 52.5% of the activity with alpha-D-galactose Akkermansia muciniphila ADP + alpha-D-glucose 1-phosphate
-
 ?
ATP + D-glucose 52.5% of the activity with alpha-D-galactose Akkermansia muciniphila ATCC BAA-835 ADP + alpha-D-glucose 1-phosphate
-
 ?
ATP + N-acetyl-D-galactosamine 15.5% of the activity with alpha-D-galactose Akkermansia muciniphila ADP + N-acetyl-alpha-D-galactosamine 1-phosphate
-
 ?
ATP + N-acetyl-D-galactosamine 15.5% of the activity with alpha-D-galactose Akkermansia muciniphila ATCC BAA-835 ADP + N-acetyl-alpha-D-galactosamine 1-phosphate
-
 ?

Synonyms

Synonyms Comment Organism
GalKAmu
-
 Akkermansia muciniphila

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
42
-
-
 Akkermansia muciniphila

Temperature Range [°C]

Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
37 60 37°C: about 65% of maximal activity, 60°C: about 55% of maximal activity Akkermansia muciniphila

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
-
 Akkermansia muciniphila