Literature summary for 2.7.1.59 extracted from

Weihofen, W.A.; Berger, M.; Chen, H.; Saenger, W.; Hinderlich, S.
Structures of human N-acetylglucosamine kinase in two complexes with N-acetylglucosamine and with ADP/glucose: insights into substrate specificity and regulation (2006), J. Mol. Biol., 364, 388-399.

Search for more literature for 2.7.1.59

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli strain BL21 (DE3)	Homo sapiens

Crystallization (Commentary)

Crystallization (Comment)	Organism
in 100 mM HEPES (pH 7.0), 100 mM NaCl, 8% (w/v) PEG 4000 and 2 mM N-acetyl-D-glucosamine	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q9UJ70	-	-

Purification (Commentary)

Purification (Comment)	Organism
glutathione Sepharose column chromatography, MonoQ HR 5/5 column chromatography, and Superdex75 gel filtration	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + N-acetyl-D-glucosamine	-	Homo sapiens	ADP + N-acetyl-D-glucosamine 6-phosphate	-	?

Subunits

Subunits	Comment	Organism
homodimer	x-ray crystallography	Homo sapiens

Synonyms

Synonyms	Comment	Organism
GlcNAc kinase	-	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
ATP	-	Homo sapiens

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Release 2023.1 (January 2023)