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Literature summary for 2.7.1.52 extracted from

  • Zeitler, R.; Danneschewski, S.; Lindhorst, T.; Thiem, J.; Reutter, W.
    Inhibition of L-fucokinase from rat liver by L-fucose analogues in vitro (1997), J. Enzyme Inhib., 11, 265-273.
    View publication on PubMed
Search for more literature for 2.7.1.52

Inhibitors

Inhibitors Comment Organism Structure
1,1,1-trichlorethyl 6-deoxy-alpha-L-galactopyranoside 10 mM, 87% inhibition Rattus norvegicus
4,6-dideoxy-4-azido-alpha-L-glucopyranose 10 mM, 9% inhibition Rattus norvegicus
4,6-dideoxy-4-fluoro-L-gluco-pyranose 10 mM, 30% inhibition Rattus norvegicus
4,6-dideoxy-4-iodo-L-glucopyranose 10 mM, 75% inhibition Rattus norvegicus
4,6-dideoxy-L-xylo-hexopyranose 10 mM, 74% inhibition Rattus norvegicus
methyl 3,6-dideoxy-alpha-L-xylo-hexopyranoside 10 mM, 17% inhibition Rattus norvegicus
methyl 4,6-dideoxy-4-iodo-alpha-L-glucopyranoside 10 mM, 54% inhibition Rattus norvegicus
methyl 4,6-dideoxy-alpha-L-xylo-hexopyranoside 10 mM, 9% inhibition Rattus norvegicus
methyl 6-deoxy-2-O-dodecanoyl-alpha-L-galactopyranoside 10 mM, 37% inhibition Rattus norvegicus
methyl 6-deoxy-alpha-L-galactopyranoside 10 mM, 89% inhibition Rattus norvegicus
octyl 6-deoxy-alpha-L-galactopyranoside 10 mM, 40% inhibition Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 6-deoxy-L-galactose
-
 Rattus norvegicus ADP + 6-deoxy-L-galactose 1-phosphate
-
 ?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.5
-
 4,6-dideoxy-L-xylo-hexopyranose pH 7.4, 37°C Rattus norvegicus
1.1
-
 methyl 6-deoxy-alpha-L-galactopyranoside pH 7.4, 37°C Rattus norvegicus
5
-
 4,6-dideoxy-4-iodo-L-glucopyranose pH 7.4, 37°C Rattus norvegicus
5.5
-
 1,1,1-trichlorethyl 6-deoxy-alpha-L-galactopyranoside pH 7.4, 37°C Rattus norvegicus