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Literature summary for 2.7.1.48 extracted from

  • Malami, I.; Abdul, A.B.; Abdullah, R.; Bt Kassim, N.K.; Waziri, P.; Christopher Etti, I.
    In silico discovery of potential uridine-cytidine kinase 2 inhibitors from the rhizome of Alpinia mutica (2016), Molecules, 21, 417.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.1.48

Inhibitors

Inhibitors Comment Organism Structure
5-fluorouracil
-
 Homo sapiens
alpinetin
-
 Homo sapiens
CTP
-
 Homo sapiens
flavokawain B
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + uridine Homo sapiens
-
 ADP + UMP
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9BZX2
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HT-29 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 5-fluorouridine
-
 Homo sapiens ADP + 5-fluoro-UMP
-
 ?
ATP + uridine
-
 Homo sapiens ADP + UMP
-
 ?

Synonyms

Synonyms Comment Organism
UCK2
-
 Homo sapiens
uridine-cytidine kinase 2
-
 Homo sapiens

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.00000003463
-
 at 37°C, pH not specified in the publication Homo sapiens CTP
0.0003214
-
 at 37°C, pH not specified in the publication Homo sapiens alpinetin
0.0006181
-
 at 37°C, pH not specified in the publication Homo sapiens flavokawain B