Literature summary for 2.7.1.45 extracted from

Mathews, I.I.; McMullan, D.; Miller, M.D.; Canaves, J.M.; Elsliger, M.; Floyd, R.; Grzechnik, S.K.; Jaroszewski, L.; Klock, H.E.; Koesema, E.; Kovarik, J.S.; Kreusch, A.; Kuhn, P.; McPhillips, T.M.; Morse, A.T.; Quijano, K.; Rife, C.L.; Schwarzenbacher, R
Crystal structure of 2-keto-3-deoxygluconate kinase (TM0067) from Thermotoga maritima at 2.05 A resolution (2007), Proteins Struct. Funct. Bioinform., 70, 603-608.

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Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Thermotoga maritima

Crystallization (Commentary)

Crystallization (Comment)	Organism
2.05 A resolution. Comparison with structure of Thermus thermophilus	Thermotoga maritima

Organism

Organism	UniProt	Comment	Textmining
Thermotoga maritima	Q9WXS2	-	-

Purification (Commentary)

Purification (Comment)	Organism
recombinant protein	Thermotoga maritima

Reaction

Reaction	Comment	Organism	Reaction ID
ATP + 2-dehydro-3-deoxy-D-gluconate = ADP + 2-dehydro-3-deoxy-6-phospho-D-gluconate	reaction is initiated by the deprotonation of the hydroxyl group of the substrate by the catalytic base Asp280. A nucleophilic attack on the gamma-phosphate of ATP by the negatively charged hydroxyl group generates the transition state intermediate	Thermotoga maritima	a

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Release 2023.1 (January 2023)