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Literature summary for 2.7.1.40 extracted from

  • Haug, U.; Hundt, S.; Brenner, H.
    Sensitivity and specificity of faecal tumour M2 pyruvate kinase for detection of colorectal adenomas in a large screening study (2008), Br. J. Cancer, 99, 133-135.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine determination of the performance characteristics of the tumour M2 pyruvate kinase test with respect to colorectal adenomas in the target population. Median tumour M2 pyruvate kinase level in the whole study population was 1.3 U/ml. At a cutoff of 4 U/ml. sensitivity is 22% and 23% for detection of advanced and other adenomas, respectively, whereas specificity is 82%. In conclusion, the tumour M2 pyruvate kinase test has only very limited potential to distinguish between people bearing precursors to colorectal cancer and people with no finding at colonoscopy Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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patients with colorectal adenomas
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