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Literature summary for 2.7.1.39 extracted from

  • Finkelnburg, B.; Klemme, J.H.
    Homoserine kinase from phototrophic bacterium Rhodospirillum rubrum is not sensitive to feedback inhibition by L-Thr (1987), FEMS Microbiol. Lett., 48(1-2), 93-96.
No PubMed abstract available
Search for more literature for 2.7.1.39

Activating Compound

Activating Compound Comment Organism Structure
L-Cys slight activation Rhodospirillum rubrum

Inhibitors

Inhibitors Comment Organism Structure
L-aspartate slight Rhodospirillum rubrum

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.44
-
 ATP pH 8, 28°C Rhodospirillum rubrum
3
-
 L-homoserine pH 8, 28°C Rhodospirillum rubrum

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
145000
-
 gel filtration Rhodospirillum rubrum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-homoserine Rhodospirillum rubrum enzyme of L-Thr synthesis ADP + O-phospho-L-homoserine
-
 ?
ATP + L-homoserine Rhodospirillum rubrum S1 enzyme of L-Thr synthesis ADP + O-phospho-L-homoserine
-
 ?

Organism

Organism UniProt Comment Textmining
Rhodospirillum rubrum
-
-
-
Rhodospirillum rubrum S1
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rhodospirillum rubrum

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-homoserine
-
 Rhodospirillum rubrum ADP + O-phospho-L-homoserine
-
 ?
ATP + L-homoserine enzyme of L-Thr synthesis Rhodospirillum rubrum ADP + O-phospho-L-homoserine
-
 ?
ATP + L-homoserine
-
 Rhodospirillum rubrum S1 ADP + O-phospho-L-homoserine
-
 ?
ATP + L-homoserine enzyme of L-Thr synthesis Rhodospirillum rubrum S1 ADP + O-phospho-L-homoserine
-
 ?