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Literature summary for 2.7.1.35 extracted from

  • di Salvo, M.L.; Nogues, I.; Parroni, A.; Tramonti, A.; Milano, T.; Pascarella, S.; Contestabile, R.
    On the mechanism of Escherichia coli pyridoxal kinase inhibition by pyridoxal and pyridoxal 5-phosphate (2015), Biochim. Biophys. Acta, 1854, 1160-1166.
    View publication on PubMed
Search for more literature for 2.7.1.35

Protein Variants

Protein Variants Comment Organism
K229Q the mutant enzyme is not inhibited by pyridoxal Escherichia coli

Inhibitors

Inhibitors Comment Organism Structure
pyridoxal
-
 Escherichia coli
pyridoxal 5'-phosphate
-
 Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + pyridoxal Escherichia coli
-
 ADP + pyridoxal 5'-phosphate
-
 ?
ATP + pyridoxal Escherichia coli BW25113
-
 ADP + pyridoxal 5'-phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Escherichia coli BW25113
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA agarose column chromatography Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + pyridoxal
-
 Escherichia coli ADP + pyridoxal 5'-phosphate
-
 ?
ATP + pyridoxal
-
 Escherichia coli BW25113 ADP + pyridoxal 5'-phosphate
-
 ?

Synonyms

Synonyms Comment Organism
Plk1
-
 Escherichia coli