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Literature summary for 2.7.1.32 extracted from
- Purification and characterization of choline/ethanolamine kinase from rat liver (1990), J. Biol. Chem., 265, 414-422.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| ethanolamine | - |
Rattus norvegicus |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | - |
Rattus norvegicus |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 47000 | - |
4 * 47000, SDS-PAGE | Rattus norvegicus |
| 160000 | - |
gel filtration | Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + choline | Rattus norvegicus | enzyme of the CDP-choline pathway of lecithin biosynthesis | ADP + O-phosphocholine | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| isoforms: CK I, CK II | Rattus norvegicus |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| ATP + choline = ADP + phosphocholine | choline kinase and ethanolamine kinase activities reside on the same protein and occur at the same active site | Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 143 | - |
pH 8.5, 37°C | Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + choline | - |
Rattus norvegicus | ADP + O-phosphocholine | - |
? | |
| ATP + choline | enzyme of the CDP-choline pathway of lecithin biosynthesis | Rattus norvegicus | ADP + O-phosphocholine | - |
? | |
| ethanolamine + ATP | - |
Rattus norvegicus | ADP + ethanolamine phosphate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| tetramer | 4 * 47000, SDS-PAGE | Rattus norvegicus |
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